Uncoupling of ATP-mediated Calcium Signaling and Dysregulated IL-6 Secretion in Dendritic Cells by Nanomolar Thimerosal
نویسندگان
چکیده
a) Running Title: Nanomolar thimerosal dysregulates DC signaling. of Rheumatology, Allergy and Clinical Medicine, UCD) for helpful discussions and for reviewing on the manuscript. declare they have no competing financial interests.
منابع مشابه
Uncoupling of ATP-Mediated Calcium Signaling and Dysregulated Interleukin-6 Secretion in Dendritic Cells by Nanomolar Thimerosal
Dendritic cells (DCs) , a rare cell type widely distributed in the soma, are potent antigen-presenting cells that initiate primary immune responses. DCs rely on intracellular redox state and calcium (Ca2+) signals for proper development and function, but the relationship between these two signaling systems is unclear. Thimerosal (THI) is a mercurial used to preserve vaccines and consumer produc...
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